@Lindi Thank you for the warm welcome. 
Is a secondary device / rPi required?
You will need a Raspberry Pi or similar device running Linux with Signal K server. Check: signalk.*org
Even though there is an option to install Venus OS large on the Cerbo, as far as I understand this is mainly to deliver data from the Cerbo. AFAIK you cant install plugins as on a Raspberry Pi.
You then want to connect your boat’s communication bus, like NMEA 200. The standard interface would be the Actisense NGT-1: actisense.*com/products/ngt-1-nmea-2000-to-pc-interface/
Once you have Signal K on your boat, you would not want to miss it’s universal communication options any more.
What OS is required on secondary device, venusOS large with Signal-K or other?
Debian Linux, wich is called raspberry Pi OS. See raspberrypi.*com/software/
Does this work Node-RED enabled on primary Cerbo GX?
It is sending data for virtual devices directly to Cerbo GX Venus OS via dbus. No Node-RED used. I made the plugin, as Node-RED felt too much overhead to me.
You need to enable D-Bus over TCP on the Cerbo GX as described in the readme: https://www.npmjs.com/package/signalk-to-venus
If you get the AC Unit connected to Signal K (assuming we are talking about air-condition, not AC power supply), you can map its controls to a virtual switch in Signal K. This switch could be switched via the Cerbo GX. Check for Signal K connection and plugins for your AC: https://www.npmjs.com/search?q=signalk-node-server-plugin
Switches are available in the new Venus OS beta. I am working on implementing these to my plugin.
This could be your solution. Adding an individual GUI for the Venus is not possible, AFAIK.
(Sorry for the disabled links. I needed to add * to the domain names, as I am allowed to only post two links for now.)